产品货号：
Z33852
中文名称：
SATB1抗体
英文名称：
Anti-SATB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SATB1 Antibody |
| 指标别名 | DNA binding protein SATB1;SATB homeobox 1;SATB1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | SATB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human SATB1 |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SATB1 (special AT-rich sequence-binding protein-1) is a protein which in humans is encoded by the SATB1 gene.SATB1,the global chromatin organizer and transcription factor,has emerged as a key factor integrating higher-order chromatin architecture with gene regulation.Recent studies have unraveled the role of SATB1 in organization of chromatin 'loopscape' and its dynamic nature in response to physiological stimuli.At genome-wide level,SATB1 seems to play a role in organization of the transcriptionally poised chromatin.SATB1 organizes the MHC class-I locus into distinct chromatin loops by tethering MARs to nuclear matrix at fixed distances.Silencing of SATB1 mimics the effects of IFN-γ treatment on chromatin loop architecture of the MHC class I locus and altered expression of genes within the locus.SATB1 has also been shown to induce breast cancer tumor growth and metastasis through the altered expression of large numbers of genes. |
| Uniprot ID | Q01826 |
| 基因名全称 | DNA-binding protein SATB1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
相关搜索：SATB1抗体，SATB1单抗，Anti-SATB1 Antibody